In our previous blog, we discussed the Endocannabinoid System (ECS); its specific functions, and the special relationship it has with substances such as CBD. In order to truly understand and appreciate the delicate balance of the ECS, we need to dive further into its vital components, all of which start and end with (you guessed it): Endocannabinoids.
Keep reading as we break down the discovery of Endocannabinoids, the different kinds, their functions, and how you can best access their wondrous power.
What is an endocannabinoid?
The best thing about endocannabinoids is: they’re in all of us! Endocannabinoids are present within our body as lipid-based neurotransmitters that bind to cannabinoid receptors. They exist in our brains, immune cells, glands, organs, and even our connective tissues. Endocannabinoids are essentially responsible for the body’s homeostasis, both internally and on a cellular level.
The discovery of cannabinoid receptors in 1990 by a team of scientists at the National Institute of Mental Health was a monumental step in uncovering and exploring the endocannabinoid system. These initial findings yielded the discovery of the first endocannabinoid: anandamide. In 1992, a team at the Hebrew University of Jerusalem discovered the second major endocannabinoid: 2-arachidonoylglycerol (2-AG). Keep reading as we discuss the two major endocannabinoids in more detail.
Anandamide is appropriately named after the Sanskrit words “andanda” which implies happiness, ultimate joy, and bliss. It is a neurotransmitter that is produced in the brain; anandamide works together with cannabinoid receptors, working to achieve and maintain bodily homeostasis. Furthermore, it is a highly potent endogenous agonist of the CB1 and CB2 receptors.
2-Arachidonoylglycerol (2-AG) is the second endocannabinoid discovered by scientists at the Hebrew University of Jerusalem. 2-AG is predominantly present in the brain and peripheral tissues. It is an agonist of both receptors CB1 and CB2, but is the primary binding molecule for the CB2 receptor. Similar to anandamide, 2-AG is one of the most abundantly found endocannabinoids found in the body, and has been known to positively affect appetite, pain management, and immune system functions.
VEDA Event Spotlight Recap
100 Years Bentley Rally
We were proud to be an official sponsor of the 100 Years Bentley Rally, that happened on August 7 to the 20th in the Santa Barbara/Napa/Pebble Beach, California area. We celebrated this momentous milestone with the best food, entertainment, and luxury hotels this beautiful part of the US has to offer.
Lake Placid Summit Classic
We’re were also very excited to be an official sponsor at the Lake Placid Summit Classic Lacrosse gathering that happened on August 5-1. Summit Lacrosse is a leader in nationwide lacrosse events and programs for boys, girls, men and women, with emphasis on responsibility and sustainability of the game. Their main goal is the development of life skills, alongside athletic skills, not just competition. We were proud to sponsor the Ackey Bones team.
Sauce on the Sand (presented by Hotbox Hockey)
In gorgeous St. Louis, Missouri on August 4th we sponsored this awesome event that featured live music, prizes, food and a great atmosphere to enjoy some slick shots on the beach. Contestants tested their skills against other worthy competitors while enjoying delicious drinks in the sunshine. We’re proud to have offered some great VEDA CBD prize packages!